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Nobel winners back global appeal
for research into neglected diseases

London / AFP

06/10/2005


Fifteen Nobel laureates on Wednesday helped launch a global campaign to demand three billion dollars to fund new research into "neglected diseases" ranging from AIDS to leishmaniasis that each day claim 35,000 lives.

The advocacy effort turned the spotlight on half a dozen diseases that hit poor countries in particular and for which new drugs, tests and vaccines are urgently needed.

It said that three billion dollars a year were needed for research in these diseases, a drop in the ocean compared with the more than 106 billion dollars annually spent on health research around the world.

The list of research "orphans" is headed by AIDS, malaria and tuberculosis (TB).
These three are well-known diseases whose cause has been taken up by the Global Fund, which focuses however on distributing the drugs to combat them rather than on researching new ones.

In addition, most of the existing treatments are inadequate or at risk of drug resistance as the pathogen mutates. And they sometimes require a complex regimen of pill-taking.

Another problem is that vaccine research into all three diseases is meagre, given the poor incentive for pharmaceutical giants to get involved in prevention rather than treatment.

Other neglected diseases named by the campaign are sleeping sickness, leishmaniasis and chagas disease, which are rampant in poor tropical countries of Africa or Latin America.

The campaign is spearheaded by a Geneva group, Drugs for Neglected Diseases Initiative (DNDi).